• PhenX, led by RTI International and funded by the National Human Genome Research Institute (NHGRI) with co-funding by the National Institute on Drug Abuse (NIDA), is helping to integrate genetics and epidemiologic research.
  • The PhenX Toolkit includes nearly 800 measurement protocols addressing 25 research domains and providing additional depth in specific research domains.
  • PhenX uses a consensus process and considers input from the scientific community on proposed measures. For each research domain, up to 15 measures are selected for inclusion in the Toolkit.
  • The PhenX Toolkit provides well-established, high-quality, low-burden measurement protocols intended for use in biomedical, epidemiological, clinical, translational, and genomic research.
  • Widespread adoption of PhenX measurement protocols will greatly facilitate cross-study comparisons and analyses.
The web-based PhenX Toolkit is available to the public and is intended for use by investigators who are designing or expanding genomics-based studies. There is no fee for using the PhenX Toolkit: www.phenxtoolkit.org
A Steering Committee (SC) of distinguished experts from the scientific community guides the selection of the measurement protocols and promotes their use. Research domains include phenotypes and environmental exposures.
Working Groups (WGs) are assembled for each research domain. Each WG uses a consensus-based process to select up to 15 measures for inclusion in the Toolkit. As part of the process, the scientific community provides feedback on the protocols; this input is considered by the WGs during their deliberations.
Expert Review Panels (ERPs), consisting of experts in the field, conduct rolling reviews of domain-specific content in the Toolkit to ensure that protocols remain highly relevant, useful to the scientific community and reflective of current science.